Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400320 | 0.72 | NOTUM (0.60) | NOTUML3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL31229471 | 0.72 | NOTUM (0.60) | NOTUML3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL28363517 | 0.72 | KDM4E (0.50) | NOTUML3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL15358169 | 0.71 | NOTUM (0.49) | NOTUML3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL22833046 | 0.70 | KDM4E (0.54) | L3MBTL1LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL23826367 | 0.70 | NOTUM (0.53) | NOTUML3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL816310 | 0.70 | NOTUM (0.57) | NOTUML3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL1705136 | 0.70 | TSHR (0.40) | LMNAKDM4EPOLBGAAALDH1A1 | |
| SCHEMBL16709806 | 0.70 | KMT2A (0.54) | L3MBTL1LMNAKDM4ENFKB1NFKB2 | |
| SCHEMBL14012580 | 0.69 | NOTUM (0.64) | NOTUML3MBTL1LMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916238-A | Compositions and methods for inhibiting RAS | 瑟拉斯有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117157290-A | Compositions and methods for inhibiting KRAS | 瑟拉斯有限公司 | 2023-12-01 | — | — | CN | disclosed |