Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6474971 | 0.91 | LMNA (0.41) | TSHRALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL1704930 | 0.77 | LCK (0.42) | TSHRALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL25285357 | 0.77 | ALDH1A1 (0.40) | TSHRALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4827078 | 0.75 | HSD17B10 (0.47) | TSHRALDH1A1LMNACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL6474180 | 0.71 | LMNA (0.39) | TSHRALDH1A1LMNAMAPTPOLB | |
| SCHEMBL1705411 | 0.70 | CNR2 (0.39) | ALDH1A1CYP1A2KDM4EGLA | |
| Hydrochloric Acid SCHEMBL6476103 | 0.70 | ITGB1 (0.38) | TSHRALDH1A1LMNAITGB1ITGA4 | |
| SCHEMBL27981307 | 0.70 | HTT (0.49) | TSHRALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL29141010 | 0.70 | NOTUM (0.46) | TSHRALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL27764491 | 0.69 | ALDH1A1 (0.42) | TSHRALDH1A1LMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518936-B2 | Method for preparing acid addition salts of polyacidic basic compounds | KOWA CO., LTD. (JP) | 2013-08-27 | — | — | US | disclosed |
| EP-1627875-B1 | METHOD FOR PRODUCING CYCLIC DIAMINE DERIVATIVE OR SALT THEREOF | KOWA CO (JP) | 2013-07-31 | — | — | EP | disclosed |
| CN-102702171-A | Process for producing acid adduct salt of polyacidic base compound | KOWA CO | 2012-10-03 | — | — | CN | disclosed |
| CN-1753886-B | Method for producing acid addition salt of polybasic base compound | KOWA CO | 2012-07-18 | — | — | CN | disclosed |
| EP-1598346-B1 | PROCESS FOR PRODUCING ACID ADDUCT SALT OF POLYACIDIC BASE COMPOUND | KOWA CO (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-20100234599-A1 | METHOD FOR PREPARING ACID ADDITION SALTS OF POLYACIDIC BASIC COMPOUNDS | KOWA CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-7750150-B2 | Process for producing acid adduct salt of polyacidic base compound | KOWA CO., LTD. (JP) | 2010-07-06 | — | — | US | disclosed |
| US-7459552-B2 | Method for producing cyclic diamine derivative or salt thereof | KOWA CO., LTD. (JP) | 2008-12-02 | — | — | US | disclosed |
| US-20060293519-A1 | Method for producing cyclic diamine derivative or salt thereof | KOWA CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| US-20060079688-A1 | Process for producing acid adduct salt of polyacidic base compound | KOWA CO., LTD. (JP) | 2006-04-13 | — | — | US | disclosed |
| CN-1753886-A | Method for producing acid addition salt of polybasic base compound | KOWA CO (JP) | 2006-03-29 | — | — | CN | disclosed |
| EP-1627875-A1 | METHOD FOR PRODUCING CYCLIC DIAMINE DERIVATIVE OR SALT THEREOF | Kowa Co., Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
| EP-1598346-A1 | PROCESS FOR PRODUCING ACID ADDUCT SALT OF POLYACIDIC BASE COMPOUND | Kowa Co., Ltd. (JP) | 2005-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234599-A1 | METHOD FOR PREPARING ACID ADDITION SALTS OF POLYACIDIC BASIC COMPOUNDS | PGA5, NAAA, CA6 | TSHR 4702/4885ALDH1A1 1557/4885LMNA 950/4885 |
| US-20060293519-A1 | Method for producing cyclic diamine derivative or salt thereof | NNT, APRT, SAT1 | TSHR 3864/4885ALDH1A1 298/4885LMNA 4263/4885 |
| US-20060079688-A1 | Process for producing acid adduct salt of polyacidic base compound | CA5B, ASIC1, NAAA | TSHR 4829/4885ALDH1A1 1334/4885LMNA 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.