Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29141655 | 0.84 | NPC1 (0.74) | NPC1RAB9AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL4937110 | 0.82 | PRMT1 (0.66) | NPC1RAB9AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL29141649 | 0.82 | BRD4 (0.62) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL4921039 | 0.81 | PRMT1 (0.65) | NPC1RAB9AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL4921306 | 0.81 | PRMT1 (0.65) | NPC1RAB9AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL4922895 | 0.80 | PRMT1 (0.69) | NPC1RAB9AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL29501954 | 0.75 | LMNA (0.60) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL4922851 | 0.75 | PRMT1 (0.69) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL29141673 | 0.73 | HTT (0.58) | NPC1RAB9AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL3806903 | 0.72 | HTT (0.80) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430609-B | Purine derivative compound, preparation method and application thereof | 东北农业大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-117430609-A | Purine derivative compound, preparation method and application thereof | 东北农业大学 | 2024-01-23 | — | — | CN | disclosed |