Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27088549 | 0.79 | NPC1 (0.49) | NPC1KDM4EASPHKDM8MEN1 | |
| SCHEMBL29142207 | 0.78 | NPC1 (0.51) | NPC1KLKB1F2KDM4EASPH | |
| SCHEMBL27478229 | 0.75 | AKT1 (0.46) | RAB9APOLB | |
| SCHEMBL29999288 | 0.75 | NPC1 (0.40) | NPC1KLKB1F2KDM4EASPH | |
| SCHEMBL27088912 | 0.74 | POLB (0.44) | KDM4ELMNASMN1; SMN2RAB9APOLB | |
| SCHEMBL30518086 | 0.74 | FFAR1 (0.41) | NPC1KDM4EASPHKDM8MEN1 | |
| SCHEMBL25155751 | 0.73 | AKT1 (0.42) | NPC1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL31360275 | 0.73 | AKT1 (0.42) | NPC1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL30344108 | 0.73 | AKT1 (0.42) | NPC1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1715769 | 0.73 | NPC1 (0.66) | NPC1KLKB1KDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083279-A | Oxazepine compounds and their use in the treatment of cancer | 基因泰克公司 | 2023-11-17 | — | — | CN | disclosed |