Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29857768 | 1.00 | METAP1 (0.46) | METAP1ATRNAMPTRXFP1DHODH | |
| SCHEMBL29857825 | 0.85 | METAP1 (0.38) | METAP1ATRNAMPTRXFP1DHODH | |
| SCHEMBL30026311 | 0.85 | NAMPT (0.46) | METAP1ATRNAMPTRXFP1HTT | |
| SCHEMBL8984337 | 0.85 | NAMPT (0.46) | METAP1ATRNAMPTRXFP1HTT | |
| SCHEMBL4669212 | 0.85 | DHODH (0.51) | METAP1ATRDHODHHTTKMT2A | |
| SCHEMBL4351188 | 0.83 | ATR (0.56) | METAP1ATRNAMPTHTTPOLB | |
| SCHEMBL14979175 | 0.82 | METAP1 (0.44) | METAP1ATRNAMPTHTTPOLB | |
| SCHEMBL5466767 | 0.81 | LMNA (0.51) | METAP1ATRNAMPTRXFP1DHODH | |
| SCHEMBL27611635 | 0.80 | METAP1 (0.46) | METAP1ATRNAMPTPOLBKMT2A | |
| SCHEMBL2260258 | 0.80 | METAP1 (0.46) | METAP1ATRNAMPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083279-A | Oxazepine compounds and their use in the treatment of cancer | 基因泰克公司 | 2023-11-17 | — | — | CN | disclosed |