Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.47 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL29142240 | 0.94 | HSP90AA1 (0.43) | HSP90AA1KMT2ASMN1; SMN2MEN1RAD52 | |
| Oxalic Acid SCHEMBL29142268 | 0.93 | MEN1 (0.45) | HSP90AA1KMT2ASMN1; SMN2MEN1CHRM2 | |
| Oxalic Acid SCHEMBL29142314 | 0.93 | MEN1 (0.42) | HSP90AA1KMT2ASMN1; SMN2MEN1CHRM2 | |
| Bicarbonate SCHEMBL23698436 | 0.91 | ABCB11 (0.44) | HSP90AA1KMT2ASMN1; SMN2MEN1CHRM2 | |
| Bicarbonate SCHEMBL23698462 | 0.91 | ABCB11 (0.44) | HSP90AA1KMT2ASMN1; SMN2MEN1CHRM2 | |
| Bicarbonate SCHEMBL6265478 | 0.91 | ABCB11 (0.44) | HSP90AA1KMT2ASMN1; SMN2MEN1CHRM2 | |
| Bicarbonate SCHEMBL23698465 | 0.91 | ABCB11 (0.44) | HSP90AA1KMT2ASMN1; SMN2MEN1CHRM2 | |
| Bicarbonate SCHEMBL31529724 | 0.91 | ABCB11 (0.44) | HSP90AA1KMT2ASMN1; SMN2MEN1CHRM2 | |
| Bromide SCHEMBL466201 | 0.90 | HSP90AA1 (0.52) | HSP90AA1KMT2ASMN1; SMN2RAD52CHRM2 | |
| Bromide SCHEMBL574727 | 0.90 | HSP90AA1 (0.52) | HSP90AA1KMT2ASMN1; SMN2RAD52CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117440991-A | Polysiloxane composition | 默克专利有限公司 | 2024-01-23 | — | — | CN | disclosed |