Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.59 |
| ▸ | FDPS | P14324 | 17/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL35016 | 0.95 | MEN1 (0.65) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Oxalic Acid SCHEMBL29142274 | 0.94 | MEN1 (0.69) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bicarbonate SCHEMBL2127082 | 0.92 | MEN1 (0.65) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Oxalic Acid SCHEMBL29142244 | 0.92 | SMN1; SMN2 (0.70) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Oxalic Acid SCHEMBL29142360 | 0.91 | SMN1; SMN2 (0.50) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL15170575 | 0.91 | MEN1 (0.73) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bicarbonate SCHEMBL5032085 | 0.91 | SMN1; SMN2 (0.67) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Maleic Acid SCHEMBL29142267 | 0.90 | MEN1 (0.55) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL29142263 | 0.90 | MEN1 (0.71) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL23004172 | 0.89 | MEN1 (0.76) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117440991-A | Polysiloxane composition | 默克专利有限公司 | 2024-01-23 | — | — | CN | disclosed |