Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | APAF1 | O14727 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.67 |
| ▸ | FDPS | P14324 | 16/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL35016 | 0.95 | MEN1 (0.65) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Bicarbonate SCHEMBL2127082 | 0.95 | MEN1 (0.65) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Propionic Acid SCHEMBL358644 | 0.93 | MEN1 (0.63) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Glycolic Acid SCHEMBL18575076 | 0.93 | MEN1 (0.63) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Bicarbonate SCHEMBL23698461 | 0.92 | MEN1 (0.76) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Bicarbonate SCHEMBL23698459 | 0.92 | MEN1 (0.76) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Succinic Acid SCHEMBL18575092 | 0.92 | MEN1 (0.61) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Bicarbonate SCHEMBL28424269 | 0.91 | SMN1; SMN2 (0.69) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Butyric Acid SCHEMBL507693 | 0.91 | MEN1 (0.59) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Pivalate SCHEMBL18575129 | 0.91 | MEN1 (0.59) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114317027-A | Method for separating naphthenic acid from naphthenic acid-containing oil product by using ionic liquid | 中国石油大学(北京) | 2022-04-12 | — | — | CN | claimed |
| CN-114317027-B | Method for separating naphthenic acid from naphthenic acid-containing oil product by using ionic liquid | 中国石油大学(北京) | 2023-04-07 | — | — | CN | disclosed |
| CN-115611736-A | Synthetic method of high hindered phenol antioxidant 1010 | 濮阳市中原石化实业有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-114317027-A | Method for separating naphthenic acid from naphthenic acid-containing oil product by using ionic liquid | 中国石油大学(北京) | 2022-04-12 | — | — | CN | disclosed |
| CN-113620787-A | Synthetic method of fluorine-containing aromatic ether | 浙江诺亚氟化工有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-111807934-B | Preparation method of electronic-grade propylene glycol monomethyl ether and product obtained by preparation method | 山东海科创新研究院有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-111807934-A | Preparation method of electronic-grade propylene glycol monomethyl ether and product obtained by preparation method | 山东海科创新研究院有限公司 | 2020-10-23 | — | — | CN | disclosed |
| US-9862675-B1 | Method of N-formylating amines with a phosphonic anhydride | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2018-01-09 | — | — | US | disclosed |
| EP-1658262-B1 | METHOD FOR PRODUCING IONIC LIQUIDS, IONIC SOLIDS OR MIXTURES THEREOF | PROIONIC PRODUCTION OF IONIC SUBSTANCES GMBH & CO KG (AT) | 2013-02-20 | — | — | EP | disclosed |
| US-8075803-B2 | Metathesis of a a quaternary ammonium, phosphonium or sulfonium cation forming a salt of hydrogencarbonate, carbonate, monoalkylcarbonate or monoarylcarbonate; storage stablility | PROIONIC GMBH (AT) | 2011-12-13 | — | — | US | disclosed |
| US-20080251759-A1 | Method For Producing Ionic Liquids, Ionic Solids Or Mixtures Thereof | PROIONIC GMBH (AT) | 2008-10-16 | — | — | US | disclosed |
| EP-1658262-A2 | METHOD FOR PRODUCING IONIC LIQUIDS, IONIC SOLIDS OR MIXTURES THEREOF | Proionic Production of Ionic Substances GmbH & Co KEG (AT) | 2006-05-24 | — | — | EP | disclosed |
| WO-2006027069-A1 | METHOD FOR PRODUCING HETEROCYCLIC QUATERNARY AMMONIUM AND/OR GUANIDINIUM COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-16 | — | — | WO | disclosed |
| WO-2005021484-A2 | METHOD FOR PRODUCING IONIC LIQUIDS, IONIC SOLIDS OR MIXTURES THEREOF | PROIONIC PRODUCTION OF IONIC SUBSTANCES GMBH & CO KEG (AT) | 2005-03-10 | — | — | WO | disclosed |