Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876470 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1PTGDR2TSHRSMN1; SMN2 | |
| SCHEMBL29143120 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1PTGDR2TSHRSMN1; SMN2 | |
| SCHEMBL29876419 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1PTGDR2TSHRS1PR2 | |
| SCHEMBL17364436 | 0.79 | GBA1 (0.41) | KDM4EALDH1A1SMN1; SMN2S1PR4S1PR3 | |
| SCHEMBL29143122 | 0.78 | ALDH1A1 (0.38) | KDM4EALDH1A1PTGDR2TSHRS1PR2 | |
| SCHEMBL29876589 | 0.78 | ALDH1A1 (0.38) | KDM4EALDH1A1PTGDR2TSHRS1PR2 | |
| SCHEMBL29143112 | 0.78 | GBA1 (0.34) | KDM4EALDH1A1S1PR4S1PR3RAB9A | |
| SCHEMBL29143113 | 0.78 | GBA1 (0.34) | KDM4EALDH1A1S1PR4S1PR3RAB9A | |
| SCHEMBL29876357 | 0.78 | GBA1 (0.34) | KDM4EALDH1A1S1PR4S1PR3RAB9A | |
| SCHEMBL22587389 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1S1PR2S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412972-A | Selective modulators of Ataxia Telangiectasia Mutated (ATM) kinase and uses thereof | 苏州赞荣医药科技有限公司 | 2024-01-16 | — | — | CN | disclosed |