Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914558 | 0.89 | CHRNB2 (0.32) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2912292 | 0.79 | MEN1 (0.32) | MEN1BLMKMT2A | |
| SCHEMBL2916520 | 0.77 | CHRNB2 (0.32) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL24475821 | 0.68 | SLC1A2 (0.38) | MEN1BLMKMT2ACHRNB2CHRNA7 | |
| SCHEMBL2918599 | 0.68 | BCHE (0.30) | — | |
| SCHEMBL2919768 | 0.67 | SLC1A2 (0.32) | — | |
| SCHEMBL2916529 | 0.67 | PRCP (0.33) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2917294 | 0.67 | CHRNB2 (0.38) | KMT2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2914132 | 0.66 | — | — | |
| SCHEMBL2917767 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228212-B1 | PROTEIN PRESENT AT THE SURFACE OF HEMATOPOIETIC STEM CELLS OF THE LYMPHOID LINE AND OF NK CELLS, AND USES THEREOF | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-01-06 | — | — | EP | disclosed |
| WO-2006014234-A2 | NOVEL RECOMBINANT POXVIRUS COMPOSITION AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2006-02-09 | — | — | WO | disclosed |