Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914357 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4275814 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL3288053 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2942557 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6361387 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2906656 | 0.73 | ADORA2A (0.55) | ALDH1A1HPGD | |
| SCHEMBL14138147 | 0.73 | HDAC6 (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2942561 | 0.72 | HSP90AA1 (0.45) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14010824 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4268756 | 0.72 | FAP (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |