Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 18/20 | 0.51 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29143902 | 0.95 | CD274 (0.48) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL27079039 | 0.93 | CD274 (0.51) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL30836557 | 0.91 | CD274 (0.50) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29143950 | 0.90 | PDCD1 (0.61) | CD274PDCD1 | |
| SCHEMBL29983091 | 0.89 | CD274 (0.54) | CD274PDCD1 | |
| SCHEMBL27078771 | 0.89 | CD274 (0.54) | CD274PDCD1 | |
| SCHEMBL27079293 | 0.88 | CD274 (0.48) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL30836129 | 0.87 | CD274 (0.57) | CD274PDCD1 | |
| SCHEMBL30836243 | 0.87 | CD274 (0.57) | CD274PDCD1 | |
| SCHEMBL30836458 | 0.87 | CD274 (0.53) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412959-A | Substituted 1-aryl-1 '-heteroaryl compounds, substituted 1,1' -biaryl compounds, and methods of use thereof | 爱彼特生物制药公司 | 2024-01-16 | — | — | CN | disclosed |