SCHEMBL29145168

SCHEMBL29145168

CC(C)c1ccc(N(C(=O)n2cnc3ccccc32)c2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.64
MAPT P10636 2/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
NPC1 O15118 1/20 0.49
ALDH1A1 P00352 1/20 0.49
RAB9A P51151 1/20 0.49
KMT2A Q03164 4/20 0.45
APAF1 O14727 1/20 0.44
ASAH1 Q13510 5/20 0.43
HTT P42858 2/20 0.43
LMNA P02545 2/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.43
MEN1 O00255 2/20 0.43
DNMT3A Q9Y6K1 1/20 0.41
TSHR P16473 1/20 0.40
STAT6 P42226 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30723140 1.00 SMN1; SMN2 (0.64) SMN1; SMN2MAPTHPGDHSD17B10NPC1
SCHEMBL30723146 0.97 SMN1; SMN2 (0.59) SMN1; SMN2MAPTHPGDHSD17B10NPC1
SCHEMBL30723151 0.89 SMN1; SMN2 (0.73) SMN1; SMN2MAPTHPGDHSD17B10NPC1
SCHEMBL29145155 0.89 SMN1; SMN2 (0.73) SMN1; SMN2MAPTHPGDHSD17B10NPC1
SCHEMBL29145112 0.81 SMN1; SMN2 (0.60) SMN1; SMN2MAPTHPGDHSD17B10NPC1
SCHEMBL30723136 0.81 SMN1; SMN2 (0.58) SMN1; SMN2MAPTHPGDHSD17B10NPC1
SCHEMBL427076 0.78 SMN1; SMN2 (1.00) SMN1; SMN2MAPTHPGDHSD17B10NPC1
SCHEMBL30723132 0.77 ALDH1A1 (0.57) SMN1; SMN2MAPTHPGDHSD17B10NPC1
SCHEMBL30723163 0.76 SMN1; SMN2 (0.58) SMN1; SMN2MAPTHPGDHSD17B10NPC1
SCHEMBL16596879 0.75 SMN1; SMN2 (0.64) SMN1; SMN2MAPTHPGDHSD17B10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed