Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | NEK2 | P51955 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500203 | 0.81 | GAA (0.54) | GAACHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL1600584 | 0.71 | KDM4E (0.76) | GAAMAPTSMN1; SMN2POLBNPSR1 | |
| SCHEMBL11132128 | 0.71 | NPC1 (0.52) | GAAMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL8990307 | 0.71 | CHEK1 (0.73) | GAACHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL29919884 | 0.71 | CHEK1 (0.73) | GAACHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL17087007 | 0.71 | KDM4E (0.48) | GAAEP300MAPTSMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL28063235 | 0.70 | KDM4E (0.73) | GAAMAPTSMN1; SMN2POLBNPSR1 | |
| SCHEMBL5449088 | 0.68 | MAPT (0.55) | GAACHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL5439415 | 0.68 | POLB (0.50) | GAAMAPTSMN1; SMN2POLBKDM4E | |
| SCHEMBL3939454 | 0.68 | F2 (0.64) | KDM4EF2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466769-A | Preparation method of organic intermediate N' - (2, 4-dichloro-5-isopropoxyphenyl) pivaloyl hydrazide | 中国科学技术大学 | 2024-01-30 | — | — | CN | claimed |
| CN-117466769-A | Preparation method of organic intermediate N' - (2, 4-dichloro-5-isopropoxyphenyl) pivaloyl hydrazide | 中国科学技术大学 | 2024-01-30 | — | — | CN | disclosed |