Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | NEK2 | P51955 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29145255 | 0.81 | GAA (0.58) | GAAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL19286172 | 0.79 | ALDH1A1 (0.47) | GAAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL30356302 | 0.79 | L3MBTL1 (0.53) | GAAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7814232 | 0.79 | L3MBTL1 (0.53) | GAAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL17281502 | 0.76 | ALDH1A1 (0.63) | GAAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL1563189 | 0.75 | GAA (0.46) | GAASMN1; SMN2KMT2AKDM4EMEN1 | |
| Trimethylammonium SCHEMBL27986322 | 0.75 | KDM4E (0.63) | GAAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL4308507 | 0.74 | CHEK1 (0.53) | GAAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11166274 | 0.73 | L3MBTL1 (0.47) | GAAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL29919884 | 0.73 | CHEK1 (0.73) | GAAALDH1A1SMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1181070-C | Urea substituted imidazoquinolines | 3M | 2004-12-22 | — | — | CN | claimed |
| EP-1198232-A4 | UREA SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2002-07-24 | — | — | EP | claimed |
| CN-1355701-A | Urea substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2002-06-26 | — | — | CN | claimed |
| EP-1198232-A1 | UREA SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2002-04-24 | — | — | EP | claimed |
| WO-2000076518-A1 | UREA SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-12-21 | — | — | WO | claimed |