SCHEMBL29145347

SCHEMBL29145347

COc1cc(Cl)cc(C(N)=O)c1Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.44
TSHR P16473 1/20 0.42
APOBEC3A P31941 1/20 0.42
HTT P42858 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CSF1R P07333 2/20 0.41
GAA P10253 4/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPT P10636 1/20 0.40
GLA P06280 2/20 0.40
ERN1 O75460 1/20 0.40
HPGD P15428 1/20 0.40
LCK P06239 1/20 0.40
FYN P06241 1/20 0.40
MAP2 P11137 1/20 0.39
LMNA P02545 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431056 0.83 GAA (0.49) KDM4EHTTMEN1KMT2AGAA
SCHEMBL8208504 0.81 KDM4E (0.45) KDM4EMEN1KMT2ACSF1RGAA
SCHEMBL12316453 0.81 ERN1 (0.53) KDM4EMEN1KMT2ACSF1RGAA
SCHEMBL29145339 0.77 ALDH1A1 (0.43) KDM4EGAAALDH1A1GLAHPGD
SCHEMBL31207306 0.75 MAPT (0.60) KDM4ETSHRMEN1KMT2AGAA
SCHEMBL726267 0.75 MAPT (0.60) KDM4ETSHRMEN1KMT2AGAA
SCHEMBL1425701 0.75 FLT1 (0.54) KDM4EMEN1KMT2ACSF1RGAA
SCHEMBL28257934 0.74 PTPN1 (0.57) KDM4ETSHRAPOBEC3AHTTAPOBEC3G
Hydrochloric Acid SCHEMBL725101 0.74 MAPT (0.58) KDM4ETSHRMEN1KMT2AGAA
SCHEMBL8744094 0.74 LCK (0.44) KDM4ETSHRAPOBEC3AHTTAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107674068-B Method for synthesizing chlorantraniliprole derivative intermediate 浙江工业大学 2023-12-19 CN disclosed