Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651163 | 0.72 | SCN4A (0.47) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL640619 | 0.67 | CYP1A2 (0.76) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL24103053 | 0.66 | MAPT (0.47) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL18424173 | 0.66 | CYP1A2 (0.73) | ALDH1A1KMT2APOLBMEN1CYP1A2 | |
| SCHEMBL19028088 | 0.65 | KMT2A (0.60) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL29145775 | 0.65 | TSHR (0.44) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL16975450 | 0.65 | SMN1; SMN2 (0.42) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL5653105 | 0.64 | POLB (0.71) | LMNAALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL22143978 | 0.64 | MAPT (0.48) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL16975404 | 0.63 | ALDH1A1 (0.52) | LMNAALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480162-A | Compounds for the treatment or prophylaxis of PRMT5 mediated diseases | 阿古诺治疗有限公司 | 2024-01-30 | — | — | CN | disclosed |