Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24710457 | 1.00 | MEN1 (0.41) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL24710450 | 0.83 | HTR6 (0.42) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL29145761 | 0.83 | HTR6 (0.42) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL21824335 | 0.79 | MEN1 (0.66) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL24710902 | 0.77 | TLR8 (0.43) | ALDH1A1PIM1PIM3PIM2HTR2B | |
| SCHEMBL29145782 | 0.77 | TLR8 (0.43) | ALDH1A1PIM1PIM3PIM2HTR2B | |
| SCHEMBL24875818 | 0.75 | KMT2A (0.39) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL30875144 | 0.74 | PARP1 (0.44) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL29231551 | 0.72 | PARP1 (0.38) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL29145770 | 0.70 | KDM6B (0.36) | KMT2AHTR2ATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480162-A | Compounds for the treatment or prophylaxis of PRMT5 mediated diseases | 阿古诺治疗有限公司 | 2024-01-30 | — | — | CN | disclosed |