Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453970 | 0.85 | SLC7A5 (0.36) | SLC7A5SMN1; SMN2LMNATDP1 | |
| Ethylene Glycol SCHEMBL27703651 | 0.79 | LTA4H (0.50) | SLC7A5LTA4HKMT2ASMN1; SMN2SLC15A1 | |
| Aspartic Acid SCHEMBL7709515 | 0.78 | SLC7A5 (0.53) | SLC7A5KIF11ALPIPKMPTGS1 | |
| Aspartic Acid SCHEMBL7709510 | 0.78 | SLC7A5 (0.53) | SLC7A5KIF11ALPIPKMPTGS1 | |
| SCHEMBL3449691 | 0.78 | NPC1 (0.50) | SLC7A5LTA4HSMN1; SMN2ESR1ESR2 | |
| SCHEMBL3449689 | 0.78 | NPC1 (0.50) | SLC7A5LTA4HSMN1; SMN2ESR1ESR2 | |
| SCHEMBL27873595 | 0.77 | LTA4H (0.54) | SLC7A5LTA4HKMT2ASMN1; SMN2SLC15A1 | |
| SCHEMBL169622 | 0.77 | LTA4H (0.54) | SLC7A5LTA4HKMT2ASMN1; SMN2SLC15A1 | |
| SCHEMBL304415 | 0.77 | LTA4H (0.54) | SLC7A5LTA4HKMT2ASMN1; SMN2SLC15A1 | |
| SCHEMBL7019120 | 0.76 | SLC7A5 (0.59) | SLC7A5LTA4HSLC15A1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869360-B | Phenylacetamides as ROCK inhibitors | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |