⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6845460 | 0.75 | — | — | |
| SCHEMBL16823348 | 0.75 | — | — | |
| SCHEMBL4074470 | 0.75 | — | — | |
| SCHEMBL9336084 | 0.75 | — | — | |
| SCHEMBL4753612 | 0.75 | — | — | |
| SCHEMBL15515122 | 0.69 | — | — | |
| SCHEMBL3920447 | 0.69 | — | — | |
| SCHEMBL4807799 | 0.68 | TDP1 (0.35) | — | |
| SCHEMBL3836449 | 0.68 | — | — | |
| SCHEMBL5156759 | 0.66 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014002110-A1 | SUBSTITUTUED PYRAZOLE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF. | RALLIS INDIA LIMITED (IN) | 2014-01-03 | — | — | WO | claimed |
| EP-0202054-B1 | PRODUCTION OF S-ARYL S-ALKYL DITHIOCARBONATES, ARENETHIOLS AND ARYTHIOETHERS | COURTAULDS PLC (GB) | 1990-07-25 | — | — | EP | claimed |
| US-4711967-A | PYROLYTICALLY ISOMERIZING AND O-ARYL S-ALKYL DITHIOCARBONATE | COURTAULDS PLC (GB) | 1987-12-08 | — | — | US | claimed |
| EP-0202054-A1 | Production of S-aryl S-alkyl dithiocarbonates, arenethiols and arythioethers | COURTAULDS PLC (GB) | 1986-11-20 | — | — | EP | claimed |
| US-20230390190-A1 | FILM FORMULATIONS CONTAINING DEXMEDETOMIDINE AND METHODS OF PRODUCING THEM | E.Z. BIOXCEL SOLUTIONS PVT. LTD. (IN) | 2023-12-07 | — | — | US | disclosed |
| US-11806429-B2 | Film formulations containing dexmedetomidine and methods of producing them | BIOXCEL THERAPEUTICS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230140624-A1 | FILM FORMULATIONS CONTAINING DEXMEDETOMIDINE AND METHODS OF PRODUCING THEM | OAKTREE FUND ADMINISTRATION, LLC | 2023-05-04 | — | — | US | disclosed |
| US-11559484-B2 | Film formulations containing dexmedetomidine and methods of producing them | BIOXCEL THERAPEUTICS, INC. (US) | 2023-01-24 | — | — | US | disclosed |
| US-11517524-B2 | Film formulations containing dexmedetomidine and methods of producing them | BIOXCEL THERAPEUTICS, INC. (US) | 2022-12-06 | — | — | US | disclosed |
| US-20220160629-A1 | FILM FORMULATIONS CONTAINING DEXMEDETOMIDINE AND METHODS OF PRODUCING THEM | OAKTREE FUND ADMINISTRATION, LLC | 2022-05-26 | — | — | US | disclosed |
| US-20220142918-A1 | FILM FORMULATIONS CONTAINING DEXMEDETOMIDINE AND METHODS OF PRODUCING THEM | OAKTREE FUND ADMINISTRATION, LLC | 2022-05-12 | — | — | US | disclosed |
| US-20210077388-A1 | FILM FORMULATIONS CONTAINING DEXMEDETOMIDINE AND METHODS OF PRODUCING THEM | OAKTREE FUND ADMINISTRATION, LLC | 2021-03-18 | — | — | US | disclosed |
| WO-1997028140-A1 | NOVEL PIPERIDINES DERIVED FROM 1-/(PIPERAZIN-1-YL)ARYL(OXY/AMINO)CARBONYL/-4-ARYL-PIPERIDINE AS SELECTIVE 5-HT1Db RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 1997-08-07 | — | — | WO | disclosed |
| EP-0584091-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF. | SCHWABE WILLMAR GMBH & CO (DE) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992018493-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1992-10-29 | — | — | WO | disclosed |
| US-5013749-A | Imidazole derivatives and their use as hypercholesterolemia and hyperlipoproteinemia agents | GLAXO GROUP LIMITED (GB) | 1991-05-07 | — | — | US | disclosed |
| EP-0202054-B1 | PRODUCTION OF S-ARYL S-ALKYL DITHIOCARBONATES, ARENETHIOLS AND ARYTHIOETHERS | COURTAULDS PLC (GB) | 1990-07-25 | — | — | EP | disclosed |
| US-4711967-A | PYROLYTICALLY ISOMERIZING AND O-ARYL S-ALKYL DITHIOCARBONATE | COURTAULDS PLC (GB) | 1987-12-08 | — | — | US | disclosed |
| EP-0202054-A1 | Production of S-aryl S-alkyl dithiocarbonates, arenethiols and arythioethers | COURTAULDS PLC (GB) | 1986-11-20 | — | — | EP | disclosed |
| EP-0030632-A2 | Benzothiazole derivatives, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GmbH (DE) | 1981-06-24 | — | — | EP | disclosed |