Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 15/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31462830 | 0.82 | NR1H2 (0.43) | NR1H2NR1H3 | |
| SCHEMBL19013553 | 0.82 | NR1H2 (0.40) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL29631893 | 0.82 | NR1H2 (0.40) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL15528336 | 0.81 | PLA2G10 (0.36) | CA12CA9 | |
| SCHEMBL30933380 | 0.81 | PLA2G10 (0.36) | CA12CA9 | |
| SCHEMBL13515301 | 0.80 | NR1H2 (0.40) | NR1H2NR1H3CA12CA9GPR119 | |
| SCHEMBL19013505 | 0.80 | NR1H2 (0.43) | NR1H2NR1H3CA12CA9GPR119 | |
| SCHEMBL28370896 | 0.79 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL15431762 | 0.76 | BACE1 (0.43) | NR1H2NR1H3CA12CA9BACE1 | |
| SCHEMBL30721531 | 0.73 | NQO2 (0.48) | NR1H2NR1H3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043314-A | Benzazepine heteroaromatic ring derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117500499-A | Substituted indole compounds and methods of use thereof | 奇努克治疗公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023246677-A1 | INDOLE-PHENYLPIPERIDINE COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 深圳信立泰药业股份有限公司 | 2023-12-28 | — | — | WO | disclosed |