Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | MITF | O75030 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909034 | 0.94 | MAPK1 (0.62) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL2911528 | 0.92 | KDM4E (0.60) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL2904502 | 0.91 | KDM4E (0.63) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL11432105 | 0.91 | KDM4E (0.63) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL11749246 | 0.88 | KDM4E (0.59) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL11275999 | 0.87 | KDM4E (0.55) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL2908421 | 0.84 | KDM4E (0.51) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL11571144 | 0.84 | KDM4E (0.51) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL7584127 | 0.84 | KDM4E (0.51) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL11272710 | 0.82 | KDM4E (0.49) | KDM4ENPC1MITFTHRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6756486-B1 | LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY | ENGELHARD CORPORATION | 2004-06-29 | — | — | US | claimed |
| EP-1668080-B1 | NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT | ENGELHARD CORP (US) | 2010-08-11 | — | — | EP | disclosed |
| US-7262284-B2 | Method for producing disazo pigments | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2007-08-28 | — | — | US | disclosed |
| US-20060167236-A1 | Method for producing disazo pigments | CLARIANT GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1668080-A1 | NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT | Engelhard Corporation (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005033212-A1 | NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT | ENGELHARD CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |
| EP-1517962-A1 | METHOD FOR PRODUCING DISAZO PIGMENTS | Clariant GmbH (DE) | 2005-03-30 | — | — | EP | disclosed |
| US-6756486-B1 | LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY | ENGELHARD CORPORATION | 2004-06-29 | — | — | US | disclosed |
| WO-2004000947-A1 | METHOD FOR PRODUCING DISAZO PIGMENTS | CLARIANT GMBH (DE) | 2003-12-31 | — | — | WO | disclosed |
| EP-1104444-B1 | STRONG GREEN-SHADE YELLOW DISAZO PIGMENT | ENGELHARD CORP (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-1104444-A1 | STRONG GREEN-SHADE YELLOW DISAZO PIGMENT | Engelhard Corporation (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009614-A1 | STRONG GREEN-SHADE YELLOW DISAZO PIGMENT | ENGELHARD CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |
| US-5889162-A | COUPLING A DIAZONIUM COMPONENT MADE FROM ONE OR MORE AROMATIC AMINES SUCH AS 2-ETHOXYANILINE WITH AT LEAST ONE COUPLING AGENT; SUITABLE FOR USE IN PLASTICS, PAINTS AND INKS | ENGELHARD CORPORATION (US) | 1999-03-30 | — | — | US | disclosed |
| EP-0581245-B1 | Water-insoluble azo colouring agents | CLARIANT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0585873-B1 | Method of preparing disazo pigments | CLARIANT GMBH (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5559216-A | AZO COUPLING | HOECHST AG (DE) | 1996-09-24 | — | — | US | disclosed |
| US-5428136-A | Water-insoluble azo colorants having two azo groups and a 1,4-bis (acetoacetylamino) benzene coupling component | HOECHST AG (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0585873-A1 | Method of preparing disazo pigments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-09 | — | — | EP | disclosed |
| EP-0581245-A1 | Water-insoluble azo colouring agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-02 | — | — | EP | disclosed |
| EP-0004611-A1 | Process for the preparation of acetoacetylaryl amides | CIBA-GEIGY AG (CH) | 1979-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167236-A1 | Method for producing disazo pigments | TYR, IPO4, CBR3 | KDM4E 3451/4885NPC1 1589/4885MITF 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.