Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 14/20 | 0.42 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149198 | 1.00 | CNR1 (0.42) | CNR1CNR2SCN9ASCN7AKCNH2 | |
| SCHEMBL29149192 | 1.00 | CNR1 (0.42) | CNR1CNR2SCN9ASCN7AKCNH2 | |
| SCHEMBL29149270 | 0.89 | CNR1 (0.43) | CNR1CNR2SCN9ASCN7AKCNH2 | |
| SCHEMBL29149252 | 0.89 | CNR1 (0.43) | CNR1CNR2SCN9ASCN7AKCNH2 | |
| SCHEMBL29149249 | 0.89 | CNR1 (0.43) | CNR1CNR2SCN9ASCN7AKCNH2 | |
| SCHEMBL29149194 | 0.89 | SCN9A (0.40) | SCN9ASCN7AKCNH2SCN5ASCN10A | |
| SCHEMBL29149311 | 0.88 | CNR2 (0.41) | CNR1CNR2SCN9APOLB | |
| SCHEMBL29149271 | 0.87 | P2RX7 (0.47) | CNR1CNR2SCN9ASCN7AKCNH2 | |
| SCHEMBL29149267 | 0.87 | P2RX7 (0.47) | CNR1CNR2SCN9ASCN7AKCNH2 | |
| SCHEMBL29149327 | 0.87 | P2RX7 (0.47) | CNR1CNR2SCN9ASCN7AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323338-B1 | TEAD INHIBITORS | ORION CORP (FI) | 2025-10-08 | — | — | EP | claimed |
| EP-4323338-A1 | TEAD INHIBITORS | Orion Corporation (FI) | 2024-02-21 | — | — | EP | claimed |
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | claimed |
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | claimed |
| EP-4323338-A1 | TEAD INHIBITORS | Orion Corporation (FI) | 2024-02-21 | — | — | EP | disclosed |
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | disclosed |