Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009343 | 1.00 | TPMT (0.40) | TPMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5210174 | 0.88 | TPMT (0.43) | TPMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31172071 | 0.84 | SMN1; SMN2 (0.40) | TPMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4182654 | 0.84 | SMN1; SMN2 (0.40) | TPMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13981896 | 0.84 | TPMT (0.40) | TPMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15561620 | 0.82 | ALDH1A1 (0.38) | TPMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4198069 | 0.80 | GRM8 (0.40) | TPMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4198067 | 0.80 | GRM8 (0.40) | TPMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24088153 | 0.79 | DBH (0.44) | ALDH1A1TUBB1KDM4EMAPTHTT | |
| SCHEMBL6370869 | 0.78 | TPMT (0.45) | TPMTGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |