Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 11/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.35 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29938542 | 1.00 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DSLC5A1 | |
| SCHEMBL24750189 | 0.89 | SLC5A1 (0.36) | PDE4APDE4BPDE4CPDE4DSLC5A1 | |
| SCHEMBL24749754 | 0.77 | RXFP1 (0.37) | PDE4APDE4BPDE4CPDE4DRXFP1 | |
| SCHEMBL29149358 | 0.73 | SCN9A (0.49) | SLC5A1 | |
| SCHEMBL24749710 | 0.71 | RXFP1 (0.34) | PDE4APDE4BPDE4CPDE4DRXFP1 | |
| SCHEMBL31009381 | 0.71 | RXFP1 (0.34) | PDE4APDE4BPDE4CPDE4DRXFP1 | |
| SCHEMBL24749658 | 0.71 | RXFP1 (0.34) | PDE4APDE4BPDE4CPDE4DRXFP1 | |
| Hydrochloric Acid SCHEMBL31694844 | 0.70 | RXFP1 (0.33) | PDE4APDE4BPDE4CPDE4DRXFP1 | |
| SCHEMBL24749996 | 0.66 | P2RX7 (0.33) | KDM1A | |
| SCHEMBL29938408 | 0.66 | P2RX7 (0.33) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |