Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 7/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149805 | 1.00 | HTR1A (0.42) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29924779 | 1.00 | HTR1A (0.42) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29924324 | 1.00 | HTR1A (0.42) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29149819 | 1.00 | HTR1A (0.42) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL24186719 | 0.89 | SLC6A2 (0.40) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29149854 | 0.89 | SLC6A2 (0.40) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29924538 | 0.89 | SLC6A2 (0.40) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL24186474 | 0.89 | SLC6A2 (0.40) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29924559 | 0.89 | SLC6A2 (0.40) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29924273 | 0.89 | SLC6A2 (0.40) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |