Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 14/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150308 | 0.93 | NPBWR1 (0.41) | NPBWR1LMNAMAPTALDH1A1HPGD | |
| SCHEMBL27077806 | 0.82 | NPBWR1 (0.42) | NPBWR1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL27435541 | 0.79 | NPBWR1 (0.43) | NPBWR1LMNAMAPTALDH1A1HPGD | |
| SCHEMBL27077886 | 0.75 | NPBWR1 (0.42) | NPBWR1LMNAMAPTALDH1A1HPGD | |
| SCHEMBL27077642 | 0.73 | NPBWR1 (0.49) | NPBWR1MCHR1AURKAAURKB | |
| SCHEMBL27435536 | 0.71 | NPBWR1 (0.43) | NPBWR1LMNAMAPTALDH1A1HPGD | |
| SCHEMBL27077786 | 0.71 | NPBWR1 (0.43) | NPBWR1MCHR1CYP11B1CYP11B2 | |
| SCHEMBL27435547 | 0.71 | NPBWR1 (0.53) | NPBWR1MCHR1AURKAAURKB | |
| SCHEMBL27077803 | 0.69 | NPBWR1 (0.56) | NPBWR1MCHR1AURKAAURKB | |
| SCHEMBL29987354 | 0.68 | NPBWR1 (0.41) | NPBWR1LMNAMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460723-A | Pharmaceutical compounds | 杜克街生物有限公司 | 2024-01-26 | — | — | CN | disclosed |