Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 6/20 | 0.41 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 3/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.34 |
| ▸ | CLK2 | P49760 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701043 | 0.81 | KDR (0.50) | PARP10PARP11CDC7MAP3K9MAP3K11 | |
| SCHEMBL30775227 | 0.81 | PDE3B (0.45) | CLK4ROCK1PIM1PARP10PARP11 | |
| SCHEMBL18170546 | 0.81 | KDR (0.50) | PARP10PARP11CDC7MAP3K9MAP3K11 | |
| SCHEMBL30775326 | 0.78 | CSF1R (0.47) | PARP10PARP11KDR | |
| SCHEMBL30775281 | 0.78 | PARP10 (0.43) | PARP10PARP11CDC7MAP3K9MAP3K11 | |
| SCHEMBL18170438 | 0.77 | CDC7 (0.40) | ROCK1PARP10PARP11CDC7MAP3K9 | |
| SCHEMBL30775395 | 0.77 | PARP10 (0.39) | PARP10PARP11CDC7MAP3K9MAP3K11 | |
| SCHEMBL29845432 | 0.73 | CLK4 (0.57) | CLK4CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL23089702 | 0.71 | PIM1 (0.44) | CLK4CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL3042262 | 0.71 | PIM1 (0.44) | CLK4CSNK1A1CDK5ROCK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295737-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-12-26 | — | — | CN | disclosed |