Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 4/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18170546 | 1.00 | KDR (0.50) | KDRPARP10PARP11CDC7PDE3B | |
| SCHEMBL3043388 | 0.86 | KDR (0.54) | KDRPARP10PARP11PDE3BPDE3A | |
| SCHEMBL18170475 | 0.83 | KDR (0.52) | KDRPDE3BPDE3ACSF1RMAP3K9 | |
| SCHEMBL3046347 | 0.83 | KDR (0.55) | KDRCSF1RMAP3K9MAP3K11KDM4E | |
| SCHEMBL18170563 | 0.83 | KDR (0.61) | KDRAURKBCSF1RMAP3K9MAP3K11 | |
| SCHEMBL18170540 | 0.83 | KDR (0.52) | KDRMAPTCSF1RMAP3K9MAP3K11 | |
| SCHEMBL29150545 | 0.81 | CLK4 (0.42) | KDRPARP10PARP11CDC7PDE3B | |
| SCHEMBL30775227 | 0.81 | PDE3B (0.45) | KDRPARP10PARP11CDC7PDE3B | |
| SCHEMBL18170608 | 0.80 | KDR (0.52) | KDRAURKBMAPTMAP3K9MAP3K11 | |
| SCHEMBL18170855 | 0.79 | KDR (0.56) | KDRPARP10PARP11AURKBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295737-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-12-26 | — | — | CN | disclosed |