Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30591168 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL1062706 | 0.88 | KMT2A (0.60) | ALDH1A1MEN1KMT2ADDR1KDM4E | |
| SCHEMBL30556195 | 0.87 | KMT2A (0.59) | ALDH1A1MEN1KMT2ADDR1KDM4E | |
| Hydrochloric Acid SCHEMBL30591154 | 0.87 | KMT2A (0.59) | ALDH1A1MEN1KMT2ADDR1KDM4E | |
| SCHEMBL29913411 | 0.83 | MEN1 (0.43) | ALDH1A1MEN1KMT2ADDR1KDM4E | |
| Trifluoroacetic Acid SCHEMBL30591159 | 0.83 | MEN1 (0.55) | ALDH1A1MEN1KMT2ADDR1KDM4E | |
| SCHEMBL29106671 | 0.80 | TSHR (0.57) | ALDH1A1MEN1KMT2ADDR1LMNA | |
| SCHEMBL23134827 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL30491310 | 0.75 | TSHR (0.37) | ALDH1A1MEN1KMT2ADDR1HSD17B10 | |
| SCHEMBL17057147 | 0.74 | DDR1 (0.41) | ALDH1A1MEN1KMT2ADDR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981661-A | Condensed ring substituted six-membered heterocyclic compound, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-10-31 | — | — | CN | disclosed |