⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15321216 | 0.72 | — | — | |
| SCHEMBL1515140 | 0.70 | — | — | |
| SCHEMBL11999050 | 0.65 | — | — | |
| SCHEMBL250247 | 0.65 | HDAC6 (0.80) | — | |
| SCHEMBL20900607 | 0.65 | GAA (0.50) | — | |
| SCHEMBL4478521 | 0.65 | HDAC8 (0.60) | — | |
| SCHEMBL3987312 | 0.65 | — | — | |
| SCHEMBL6973305 | 0.63 | — | — | |
| SCHEMBL159659 | 0.63 | HDAC2 (0.67) | — | |
| SCHEMBL24727543 | 0.62 | GAA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542526-B | Condensed imidazole derivatives substituted with tertiary hydroxyl groups as PI 3K-gamma inhibitors | 因赛特公司 | 2024-01-09 | — | — | CN | claimed |
| CN-111542526-B | Condensed imidazole derivatives substituted with tertiary hydroxyl groups as PI 3K-gamma inhibitors | 因赛特公司 | 2024-01-09 | — | — | CN | disclosed |