Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151083 | 0.91 | MET (1.00) | MET | |
| SCHEMBL30745154 | 0.91 | MET (1.00) | MET | |
| SCHEMBL29151044 | 0.85 | MET (0.61) | METBRD4USP2 | |
| SCHEMBL30745161 | 0.85 | MET (0.61) | METBRD4USP2 | |
| SCHEMBL3843640 | 0.83 | MET (0.79) | METMEN1KMT2A | |
| SCHEMBL2465372 | 0.83 | MET (0.65) | METMEN1KMT2A | |
| SCHEMBL29151080 | 0.83 | MET (0.65) | METNPC1GAAMAPTMEN1 | |
| SCHEMBL30745140 | 0.83 | MET (0.65) | METNPC1GAAMAPTMEN1 | |
| SCHEMBL2469745 | 0.79 | MET (0.60) | METMEN1KMT2A | |
| SCHEMBL30745139 | 0.79 | MET (0.84) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510470-A | Pyridazinone compounds and application thereof | 暨南大学 | 2024-02-06 | — | — | CN | disclosed |