Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | RARG | P13631 | 7/20 | 0.39 |
| ▸ | RARA | P10276 | 6/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915235 | 0.83 | RARG (0.34) | RARBRARGRARACRBNRXRA | |
| SCHEMBL3001498 | 0.82 | CRBN (0.48) | RARBRARGRARACRBNCA12 | |
| SCHEMBL2915298 | 0.81 | CRBN (0.56) | CRBN | |
| SCHEMBL2915236 | 0.81 | CRBN (0.46) | CRBN | |
| SCHEMBL1530194 | 0.78 | CRBN (0.60) | RARBRARGRARACRBNRXRA | |
| SCHEMBL2910151 | 0.78 | CRBN (0.43) | CRBNCA12CA1CA9 | |
| SCHEMBL2913339 | 0.78 | ALDH1A1 (0.34) | CRBNTNFRSF1A | |
| SCHEMBL2907863 | 0.77 | CRBN (0.42) | CRBN | |
| Methyl Alcohol SCHEMBL2913736 | 0.76 | CRBN (0.67) | CRBN | |
| Alcohol SCHEMBL2909873 | 0.76 | CRBN (0.64) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |