Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | LITAF | Q99732 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648177 | 0.87 | KCNH2 (0.37) | PRKCQGPR119METMMP1MMP3 | |
| SCHEMBL21099594 | 0.87 | KCNH2 (0.37) | PRKCQGPR119METMMP1MMP3 | |
| SCHEMBL21137338 | 0.86 | KCNH2 (0.38) | PRKCQGPR119METMMP1MMP3 | |
| SCHEMBL21099343 | 0.86 | KCNH2 (0.38) | PRKCQGPR119METMMP1MMP3 | |
| SCHEMBL21099325 | 0.85 | KCNH2 (0.37) | PRKCQGPR119METMMP1MMP3 | |
| SCHEMBL30672184 | 0.82 | NR1H2 (0.34) | GPR119KAT8KAT5 | |
| SCHEMBL21099342 | 0.82 | MET (0.38) | PRKCQGPR119METMMP1MMP3 | |
| SCHEMBL21099404 | 0.82 | KRAS (0.41) | PRKCQMETTNFLITAFMAPT | |
| SCHEMBL21050822 | 0.80 | MET (0.39) | PRKCQGPR119METMMP1MMP3 | |
| SCHEMBL21100021 | 0.80 | MET (0.39) | PRKCQGPR119METMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222654-A | KRAS G12C inhibitors and uses thereof | 苏州赞荣医药科技有限公司 | 2023-12-12 | — | — | CN | disclosed |