Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 6/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | STK17B | O94768 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30692069 | 1.00 | CES2 (0.58) | CES2MAOAMAOBTNFCYP1A2 | |
| SCHEMBL29153446 | 1.00 | CES2 (0.58) | CES2MAOAMAOBTNFCYP1A2 | |
| SCHEMBL28221178 | 0.88 | CES2 (0.77) | CES2MAOAMAOBTNFCYP19A1 | |
| SCHEMBL28221177 | 0.88 | CES2 (0.77) | CES2MAOAMAOBTNFCYP19A1 | |
| SCHEMBL30692070 | 0.84 | CES2 (0.48) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL29153443 | 0.84 | CES2 (0.48) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL29124081 | 0.84 | CES2 (0.61) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL30705798 | 0.84 | CES2 (0.61) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL29153440 | 0.84 | CES2 (0.48) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL29124085 | 0.84 | CES2 (0.61) | CES2MAOAMAOBSTK17BMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186044-A | Benzofuranone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-12-08 | — | — | CN | claimed |
| CN-117186044-A | Benzofuranone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-12-08 | — | — | CN | disclosed |