Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 12/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | TIPARP | Q7Z3E1 | 7/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.37 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29153680 | 1.00 | NPBWR1 (0.45) | NPBWR1MCHR1TIPARPHDAC1HDAC6 | |
| SCHEMBL24962321 | 0.89 | NPBWR1 (0.48) | NPBWR1MCHR1BRD4 | |
| SCHEMBL24687640 | 0.89 | NPBWR1 (0.51) | NPBWR1MCHR1BRD4 | |
| SCHEMBL24675519 | 0.89 | NPBWR1 (0.44) | NPBWR1MCHR1TIPARPHDAC1HDAC6 | |
| SCHEMBL21522519 | 0.89 | NPBWR1 (0.44) | NPBWR1MCHR1TIPARPHDAC1HDAC6 | |
| SCHEMBL26915108 | 0.89 | NPBWR1 (0.44) | NPBWR1MCHR1TIPARPHDAC1HDAC6 | |
| SCHEMBL21522522 | 0.89 | NPBWR1 (0.44) | NPBWR1MCHR1TIPARPHDAC1HDAC6 | |
| SCHEMBL24640392 | 0.89 | NPBWR1 (0.44) | NPBWR1MCHR1TIPARPHDAC1HDAC6 | |
| SCHEMBL30104870 | 0.89 | NPBWR1 (0.46) | NPBWR1MCHR1TIPARPHDAC1HDAC6 | |
| SCHEMBL21521225 | 0.87 | NPBWR1 (0.51) | NPBWR1MCHR1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022247839-A1 | PARP7 INHIBITOR | 山东轩竹医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |