Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29153761 | 1.00 | RET (0.36) | RETMEN1KMT2AALDH1A1KIF18A | |
| SCHEMBL29153755 | 0.83 | MEN1 (0.36) | MEN1KMT2AALDH1A1IRAK4MAPT | |
| SCHEMBL30862503 | 0.82 | IRAK1 (0.38) | MEN1KMT2AALDH1A1IRAK4JAK3 | |
| SCHEMBL30862497 | 0.81 | MEN1 (0.33) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29153754 | 0.80 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1IRAK4SMN1; SMN2 | |
| SCHEMBL29153750 | 0.78 | MEN1 (0.36) | MEN1KMT2AALDH1A1IRAK4SMN1; SMN2 | |
| SCHEMBL29153746 | 0.78 | MEN1 (0.36) | MEN1KMT2AALDH1A1IRAK4SMN1; SMN2 | |
| SCHEMBL30862510 | 0.77 | RET (0.39) | RETALDH1A1IRAK4MAPT | |
| SCHEMBL30862496 | 0.77 | MEN1 (0.33) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29153765 | 0.73 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510497-A | DGK zeta inhibitors | 山东轩竹医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |