Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25285309 | 0.84 | MAPT (0.41) | MAPTKDM4ELPAR1LPAR3RAB9A | |
| SCHEMBL25429029 | 0.83 | MAPT (0.41) | MAPTKDM4ELPAR1LPAR3RAB9A | |
| SCHEMBL31452200 | 0.83 | SMN1; SMN2 (0.48) | KDM4ELPAR1LPAR3RAB9ANPC1 | |
| SCHEMBL25405115 | 0.81 | MAPT (0.39) | MAPTKDM4ELPAR1LPAR3RAB9A | |
| SCHEMBL25340143 | 0.81 | LPAR1 (0.70) | MAPTKDM4ELPAR1LPAR3RAB9A | |
| SCHEMBL25340148 | 0.81 | LPAR1 (0.70) | MAPTKDM4ELPAR1LPAR3RAB9A | |
| SCHEMBL25403761 | 0.80 | MAPT (0.39) | MAPTKDM4ELPAR1LPAR3RAB9A | |
| SCHEMBL21107996 | 0.80 | POLB (0.41) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL29645215 | 0.80 | POLB (0.41) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL3711198 | 0.80 | LPAR1 (0.42) | MAPTKDM4ELPAR1LPAR3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989220-A | Amido cyclohexanoic acid derivatives as LPA receptor inhibitors | 奇斯药制品公司 | 2023-04-18 | — | — | CN | disclosed |