Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30472637 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1LPAR1LPAR3 | |
| SCHEMBL4029141 | 0.83 | LPAR1 (0.62) | SMN1; SMN2RAB9ANPC1LPAR1LPAR3 | |
| SCHEMBL31452190 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ANPC1LPAR1LPAR3 | |
| SCHEMBL29154153 | 0.83 | MAPT (0.41) | SMN1; SMN2RAB9ANPC1LPAR1LPAR3 | |
| SCHEMBL343051 | 0.83 | LPAR1 (0.56) | SMN1; SMN2RAB9ANPC1LPAR1LPAR3 | |
| SCHEMBL30472665 | 0.82 | NPC1 (0.45) | SMN1; SMN2RAB9ANPC1LPAR1LPAR3 | |
| SCHEMBL30472613 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1LPAR1LPAR3 | |
| SCHEMBL25340148 | 0.81 | LPAR1 (0.70) | RAB9ALPAR1LPAR3ALDH1A1CYP2C9 | |
| SCHEMBL25340143 | 0.81 | LPAR1 (0.70) | RAB9ALPAR1LPAR3ALDH1A1CYP2C9 | |
| SCHEMBL25340863 | 0.78 | LPAR1 (0.53) | RAB9ANPC1LPAR1LPAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066341-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066341-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | LPAR1, LPAR2, LPAR3 | SMN1; SMN2 4141/4885RAB9A 2476/4885NPC1 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.