⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850250 | 0.76 | — | — | |
| SCHEMBL1701461 | 0.76 | — | — | |
| SCHEMBL15338317 | 0.68 | — | — | |
| SCHEMBL15457844 | 0.66 | — | — | |
| SCHEMBL1899979 | 0.64 | — | — | |
| SCHEMBL7339316 | 0.64 | ALDH1A1 (0.31) | — | |
| SCHEMBL9054113 | 0.63 | — | — | |
| SCHEMBL1072385 | 0.63 | — | — | |
| SCHEMBL28246896 | 0.62 | — | — | |
| SCHEMBL28053462 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203206-A | GCN2 modulating compounds and uses thereof | 希伯塞尔股份有限公司 | 2023-12-08 | — | — | CN | disclosed |