Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPD | P32754 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30726098 | 1.00 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBCYP1A2CYP2D6 | |
| SCHEMBL30726097 | 1.00 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBCYP1A2CYP2D6 | |
| SCHEMBL31196715 | 0.89 | NPC1 (0.65) | HSD17B10SMN1; SMN2POLBCYP1A2CYP2D6 | |
| SCHEMBL1962312 | 0.87 | HSD17B10 (0.77) | HSD17B10SMN1; SMN2POLBALOX12ALOX15 | |
| SCHEMBL1682746 | 0.86 | MAPK1 (0.75) | HSD17B10SMN1; SMN2POLBALOX12ALOX15 | |
| SCHEMBL30122631 | 0.86 | MAPK1 (0.75) | HSD17B10SMN1; SMN2POLBALOX12ALOX15 | |
| SCHEMBL30726096 | 0.86 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBALOX12ALOX15 | |
| SCHEMBL29154650 | 0.86 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBALOX12ALOX15 | |
| SCHEMBL4391482 | 0.85 | MAPK1 (0.70) | HSD17B10SMN1; SMN2POLBCYP1A2CYP2D6 | |
| SCHEMBL29839759 | 0.84 | HSD17B10 (0.73) | HSD17B10SMN1; SMN2POLBALOX12ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510415-A | Synthesis method of quinazolinone compound | 中国人民解放军军事科学院防化研究院 | 2024-02-06 | — | — | CN | disclosed |