Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30122631 | 0.88 | MAPK1 (0.75) | HSD17B10SMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL1682746 | 0.88 | MAPK1 (0.75) | HSD17B10SMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL30726097 | 0.87 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL29154650 | 0.87 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBLMNAMEN1 | |
| SCHEMBL29154635 | 0.87 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL30726098 | 0.87 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL30726096 | 0.87 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBLMNAMEN1 | |
| SCHEMBL29839759 | 0.86 | HSD17B10 (0.73) | HSD17B10SMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL4959092 | 0.86 | HSD17B10 (0.73) | HSD17B10SMN1; SMN2POLBLMNAMEN1 | |
| SCHEMBL29839760 | 0.86 | HSD17B10 (0.73) | HSD17B10SMN1; SMN2POLBLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170224687-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170224687-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170224687-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC (US) | 2017-08-10 | — | — | US | disclosed |
| US-9486455-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-9486455-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-9486455-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-8552009-B2 | Substituted pyrimido 4.5-d pyrimidin-4-one compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. | 2013-10-08 | — | — | US | disclosed |
| US-20100152209-A1 | Compounds for Modulating TRPV3 Function | HYDRA BIOSCIENCES INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20090018147-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-20090018147-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-20090018147-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES INC. (US) | 2009-01-15 | — | — | US | disclosed |
| WO-2008140750-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| US-20070179164-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| US-20070179164-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| US-20070179164-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| WO-2007056124-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| CN-1708306-A | Quinazolinone compounds as calcilytics | NPS PHARMA INC (US) | 2005-12-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | TRPV3, TRPV1, TRPV4 | HSD17B10 2713/4885SMN1; SMN2 2219/4885POLB 4849/4885 |
| US-20090018147-A1 | Compounds for modulating TRPV3 function | TRPV3, TRPV1, TRPV4 | HSD17B10 2713/4885SMN1; SMN2 2219/4885POLB 4849/4885 |
| US-20100152209-A1 | Compounds for Modulating TRPV3 Function | TRPV3, TRPV1, TRPV4 | HSD17B10 2713/4885SMN1; SMN2 2219/4885POLB 4849/4885 |
| US-20070179164-A1 | Compounds for modulating TRPV3 function | TRPV3, TRPV1, TRPV4 | HSD17B10 2713/4885SMN1; SMN2 2219/4885POLB 4849/4885 |
| US-20170224687-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | TRPV3, TRPV1, TRPV4 | HSD17B10 2713/4885SMN1; SMN2 2219/4885POLB 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.