Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110406 | 0.87 | ESR1 (0.58) | HSD17B10HDAC1HDAC8HDAC6HDAC2 | |
| SCHEMBL30726096 | 0.86 | HSD17B10 (0.75) | HSD17B10POLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29154650 | 0.86 | HSD17B10 (0.75) | HSD17B10POLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30726093 | 0.85 | MAPK1 (0.70) | HSD17B10POLBALDH1A1SMN1; SMN2GRM1 | |
| SCHEMBL9336504 | 0.85 | MAPK1 (0.70) | HSD17B10POLBALDH1A1SMN1; SMN2GRM1 | |
| SCHEMBL1682746 | 0.83 | MAPK1 (0.75) | HSD17B10POLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30122631 | 0.83 | MAPK1 (0.75) | HSD17B10POLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7171020 | 0.80 | POLB (0.67) | HSD17B10HDAC1HDAC8HDAC6HDAC2 | |
| SCHEMBL22720129 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL338139 | 0.79 | ALDH1A1 (0.68) | HSD17B10ALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510415-A | Synthesis method of quinazolinone compound | 中国人民解放军军事科学院防化研究院 | 2024-02-06 | — | — | CN | disclosed |