Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342242 | 0.79 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL2091239 | 0.78 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL8924884 | 0.78 | USP1 (0.47) | MAPK13MAPK12MAPK11MAPK14L3MBTL1 | |
| SCHEMBL5537558 | 0.76 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL27216988 | 0.76 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL31194857 | 0.74 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL9949139 | 0.73 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL5592519 | 0.73 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL5994160 | 0.73 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL29580256 | 0.72 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510430-A | Oxazole compound and synthetic method and application thereof | 南昌大学 | 2024-02-06 | — | — | CN | disclosed |