Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29154737 | 0.86 | SCN5A (0.43) | SCN5ASCN9APKMPOLBKIF11 | |
| SCHEMBL28039485 | 0.82 | PARP1 (0.40) | PKMKIF11PARP1 | |
| SCHEMBL29118559 | 0.81 | KMT2A (0.48) | PKMPOLBKIF11 | |
| SCHEMBL29154732 | 0.80 | HTT (0.39) | — | |
| SCHEMBL25840100 | 0.75 | GRIN2D (0.48) | SCN5ASCN9APKMPOLBKIF11 | |
| SCHEMBL18039462 | 0.73 | OGG1 (0.39) | POLBKIF11NOS1SLC22A2SLC22A1 | |
| SCHEMBL11541397 | 0.73 | MAPT (0.60) | SCN5ASCN9APKMPOLBKIF11 | |
| SCHEMBL10876037 | 0.72 | CYP19A1 (0.42) | SCN5ASCN9APKMKIF11CYP2B6 | |
| SCHEMBL10957494 | 0.72 | CNR2 (0.38) | SCN5ASCN9A | |
| SCHEMBL6227938 | 0.72 | CYP3A4 (0.39) | KIF11PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561247-A | Novel potassium channel inhibitors | 阿塞西翁制药公司 | 2024-02-13 | — | — | CN | disclosed |