Acetoacetic Acid

Acetoacetic Acid

SCHEMBL29155166

C=C(C)C(=O)O.C=C(C)C(=O)O.CC(=O)CC(=O)O.OCCO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
KDM6B O15054 1/20 0.39
KDM5C P41229 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
PHF8 Q9UPP1 1/20 0.39
KDM2A Q9Y2K7 1/20 0.39
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TGFBR1 P36897 1/20 0.36
LDHA P00338 1/20 0.36
SRR Q9GZT4 1/20 0.36
LMNA P02545 1/20 0.35
SLC15A2 Q16348 1/20 0.35
ALDH1A1 P00352 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL28836460 1.00 KDM4E (0.39) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL5276570 1.00 KDM4E (0.39) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL6430772 0.93 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL5797432 0.91 FNTA (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL29000068 0.90 KDM4E (0.42) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL711498 0.87 KDM4E (0.48) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL2701583 0.87 KDM4E (0.48) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL27976079 0.86 TSHR (0.39) KDM4EKDM6BKDM5CEGLN1PHF8
Methacrylic Acid SCHEMBL11572945 0.84 TDP1 (0.42) HSD17B10TGFBR1LMNASLC15A2ALDH1A1
Methacrylic Acid SCHEMBL4290016 0.84 TDP1 (0.42) HSD17B10TGFBR1LMNASLC15A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874717-B Protective film for metal surface and preparation method thereof 广东东立新材料科技股份有限公司 2023-12-12 CN disclosed