Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.33 |
| ▸ | VNN1 | O95497 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30155351 | 1.00 | DDB1 (0.37) | DDB1CRBNUSP30HSD11B1GPR119 | |
| SCHEMBL30155382 | 1.00 | DDB1 (0.37) | DDB1CRBNUSP30HSD11B1GPR119 | |
| SCHEMBL29156254 | 0.80 | DPP4 (0.33) | VNN1 | |
| SCHEMBL29156257 | 0.80 | DPP4 (0.33) | VNN1 | |
| SCHEMBL29156337 | 0.80 | DPP4 (0.33) | VNN1 | |
| SCHEMBL24700145 | 0.78 | MEN1 (0.46) | USP30HSD11B1GPR119 | |
| SCHEMBL1827484 | 0.77 | HPGD (0.51) | USP30GPR119HPGD | |
| SCHEMBL23825249 | 0.77 | CHRM2 (0.41) | HSD11B1HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL5140938 | 0.77 | CHRM2 (0.45) | HSD11B1GPR119HPGDCHRM2CHRM1 | |
| SCHEMBL29156343 | 0.77 | HPGD (0.40) | DDB1CRBNUSP30HPGDCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425649-A | Pyrazole derivatives as KRAS mutein inhibitors | 诺华股份有限公司 | 2024-01-19 | — | — | CN | disclosed |