Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 3/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29156257 | 1.00 | DPP4 (0.33) | DPP4DPP8VNN1MCHR1ALDH1A1 | |
| SCHEMBL29156254 | 1.00 | DPP4 (0.33) | DPP4DPP8VNN1MCHR1ALDH1A1 | |
| SCHEMBL30155382 | 0.80 | DDB1 (0.37) | VNN1 | |
| SCHEMBL30155351 | 0.80 | DDB1 (0.37) | VNN1 | |
| SCHEMBL29156263 | 0.80 | DDB1 (0.37) | VNN1 | |
| SCHEMBL3831586 | 0.72 | DPP4 (0.43) | DPP4DPP8VNN1MCHR1PDK2 | |
| SCHEMBL22694566 | 0.72 | CNR2 (0.36) | — | |
| SCHEMBL10589014 | 0.70 | ALDH1A1 (0.39) | ALDH1A1ALOX15 | |
| SCHEMBL2990621 | 0.69 | VNN1 (0.45) | DPP4DPP8VNN1MCHR1PDK2 | |
| SCHEMBL5901127 | 0.69 | VNN1 (0.45) | DPP4DPP8VNN1MCHR1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425649-A | Pyrazole derivatives as KRAS mutein inhibitors | 诺华股份有限公司 | 2024-01-19 | — | — | CN | disclosed |