Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 20/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24792547 | 1.00 | GLP1R (0.56) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL30053945 | 1.00 | GLP1R (0.56) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL30745365 | 0.92 | GLP1R (0.51) | GLP1RCYP2C8KCNH2HTR2A | |
| SCHEMBL24792581 | 0.92 | GLP1R (0.51) | GLP1RCYP2C8KCNH2HTR2A | |
| SCHEMBL26110698 | 0.85 | GLP1R (0.71) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL26110712 | 0.85 | GLP1R (0.71) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL29642173 | 0.85 | GLP1R (0.71) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL30199987 | 0.82 | GLP1R (0.54) | GLP1RCYP2C8KCNH2HTR1A | |
| SCHEMBL24791618 | 0.81 | GLP1R (0.59) | GLP1R | |
| SCHEMBL30199788 | 0.81 | GLP1R (0.52) | GLP1RCYP2C8KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |