Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 20/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24792581 | 1.00 | GLP1R (0.51) | GLP1RCYP2C8HTR2AKCNH2 | |
| SCHEMBL29157103 | 0.92 | GLP1R (0.56) | GLP1RCYP2C8HTR2AKCNH2 | |
| SCHEMBL30053945 | 0.92 | GLP1R (0.56) | GLP1RCYP2C8HTR2AKCNH2 | |
| SCHEMBL24792547 | 0.92 | GLP1R (0.56) | GLP1RCYP2C8HTR2AKCNH2 | |
| SCHEMBL24793024 | 0.88 | GLP1R (0.51) | GLP1RCYP2C8HTR2AKCNH2 | |
| SCHEMBL24793829 | 0.88 | GLP1R (0.51) | GLP1RCYP2C8HTR2AKCNH2 | |
| SCHEMBL29157086 | 0.88 | GLP1R (0.51) | GLP1RCYP2C8HTR2AKCNH2 | |
| SCHEMBL27191387 | 0.85 | GLP1R (0.56) | GLP1RCYP2C8HTR2AKCNH2 | |
| SCHEMBL24791693 | 0.83 | GLP1R (0.53) | GLP1R | |
| SCHEMBL30745416 | 0.83 | GLP1R (0.53) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |